In Vivo Bilateral Compressive Stresses in Disc Annulus: Hemiepiphyseal Implant in Quadruped Model
ثبت نشده
چکیده
INTRODUCTION: Spine growth modification alters stress distributions in vertebral growth plates and discs, and one method has been approved for an early stage prospective clinical study. Quantification of stresses is required to help assess implant efficacy and disc health. More generally, despite widespread and necessary use of animals in preclinical studies of spine instrumentation, limited quantitative information is available on mechanobiological conditions in quadruped spines for comparisons to those of humans. The purpose of this study was to develop an in vivo model capable of determining physiological compressive stresses bilaterally in the intervertebral disc annulus, and preliminarily assess effects of a hemiepiphyseal implant.
منابع مشابه
Finite Element Study of a Lumbar Intervertebral Disc Nucleus Replacement Device
Nucleus replacement technologies are a minimally invasive alternative to spinal fusion and total disc replacement that have the potential to reduce pain and restore motion for patients with degenerative disc disease. Finite element modeling can be used to determine the biomechanics associated with nucleus replacement technologies. The current study focuses on a new nucleus replacement device de...
متن کاملMild (not severe) disc degeneration is implicated in the progression of bilateral L5 spondylolysis to spondylolisthesis
BACKGROUND Spondylolytic (or lytic) spondylolisthesis is often associated with disc degeneration at the index-level; however, it is not clear if disc degeneration is the cause or the consequence of lytic spondylolisthesis. The main objective of this computed tomography based finite element modelling study was to examine the role of different grades of disc degeneration in the progression of a b...
متن کاملPatient-specific spine models. Part 1: Finite element analysis of the lumbar intervertebral disc--a material sensitivity study.
If patient-specific finite element models of the spine could be developed, they would offer enormous opportunities in the diagnosis and management of back problems. Several generic models have been developed in the past, but there has been very little detailed examination of the sensitivity of these models' characteristics to the input parameters. This relationship must be thoroughly understood...
متن کاملThe effect of nucleus implant parameters on the compressive mechanics of the lumbar intervertebral disc: a finite element study.
A simplified finite element model of the human lumbar intervertebral disc was utilized for understanding nucleus pulposus implant mechanics. The model was used to assess the effect of nucleus implant parameter variations on the resulting compressive biomechanics of the lumbar anterior column unit. The effects of nucleus implant material (modulus and Poisson's ratio) and geometrical (height and ...
متن کاملOn the Use of Biaxial Properties in Modeling Annulus as a Holzapfel–Gasser–Ogden Material
Besides the biology, stresses and strains within the tissue greatly influence the location of damage initiation and mode of failure in an intervertebral disk. Finite element models of a functional spinal unit (FSU) that incorporate reasonably accurate geometry and appropriate material properties are suitable to investigate such issues. Different material models and techniques have been used to ...
متن کامل